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Hiromitsu Nakauchi: Stem cell technology and its potential for future medicine

Hiromitsu Nakauchi: Stem cell technology and its potential for future medicine, Ludwig Boltzmann Forum, 20 February 2020

Hiromitsu Nakauchi, Stanford University School of Medicine, Professor, and University of Tokyo, Project Professor, Divn. of Stem Cell Therapy, Institute of Medical Science

Summary by Gerhard Fasol

Summary: solving the shortage of organ donors and immune rejection with stem cells

There are far more patients requiring organ transplants than organ donations. Transplanted organs are rejected by the recipient’s immune system requiring life-long immune suppression. Professor Nakauchi explains his path towards growing organs based on a patient’s stem cells injected into an animal’s embryo, which then is implanted into a host animal, and when fully grown this organ is transplanted back into the patient. While this long term target is still very difficult and far in the future, Professor Nakauchi and his teams at Tokyo University and Stanford University have solved sever

Hiromitsu (Hiro) Nakauchi

Department of Genetics Stanford University
Career Trajectory
He isolated CD8 genes during his post-doc period at the Laboratory of Prof. Leonard Herzenberg at Stanford University. After returning to Japan, he started working on hematopoietic stem cells in his laboratory at RIKEN. In 1994, he became Professor of Immunology at the University of Tsukuba where he demonstrated that a single hematopoietic stem cell could reconstitute the entire hematopoietic system, a definitive experimental proof for the “stemness”. Since April 2002, he has been a Professor of Stem Cell Therapy in the Institute of Medical Science at The University of Tokyo (IMSUT). In 2008, he was appointed Director of newly established Center for Stem Cell Biology and Regenerative Medicine at IMSUT. Just recently, he returned to Stanford University as a faculty to continue his stem cell research at the Institute of Stem Cell Biology and Regenerative Medicine. Goals of his work are to translate discoveries in basic research into practical medical applications.

Papers共 763 篇Author

After earning medical degree from Yokohama City University School of Medicine and a PhD in immunology from the University of Tokyo Graduate School of Medicine, I traveled to Stanford to complete my postdoctoral training in the laboratory of the late Prof. Leonard Herzenberg. While there, I isolated CD8 genes that encode proteins critically important for immune cells to recognize virus-infected and cancer cells.

After returning to Japan, I started working on hematopoietic stem cells in my laboratory at the RIKEN Life Science Research Center. In 1994, I became Professor of Immunology at the University of Tsukuba, where I demonstrated that a single hematopoietic stem cell could reconstitute the entire hematopoietic system—a definitive experimental proof of its “stemness.”

Since April 2002, I have been a Professor of Stem Cell Therapy in the Institute of Medical Science at The University of Tokyo (IMSUT). In 2008, I was appointed Director of the newly established Center for Stem Cell Biology and Regenerative Medicine at IMSUT. I returned to Stanford University in 2014 as Professor o

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